Nevus Comedonicus Syndrome (NCS) (2024)

FAQs

Nevus Comedonicus Syndrome (NCS)? ›

Nevus comedonicus (NC) is characterized by a localized collection of dilated follicles containing keratin. Some authors have split this entity into NC consisting of comedo-like dilated follicular orifices and “acne nevus” which produces sebum and may be complicated by inflammation and scarring.

Persons with inflammatory nevus comedonicus can develop cysts, recurrent bacterial infections, fistulae, and abscesses, and these may subsequently heal with scarring. Treat these lesions with appropriate antibiotics or surgical drainage. Infections may be recurrent.

Nevus comedonicus syndrome is one of the epidermal nevus syndromes, but is extremely rare. There is no gender or racial difference in the prevalence of this condition. The prevalence ranges from 1 in 45,000 - 100 000.

Nevus comedonicus (NC), first described by Kofmann in 1895, is a rare condition considered to be a type of epidermal nevus. Nevus comedonicus presents as grouped, dilated follicular openings with dark keratin plugs.

Rare conditions

Nevus comedonicus or comedo nevus is a benign hamartoma (birthmark) of the pilosebaceous unit around the oil-producing gland in the skin. It has widened open hair follicles with dark keratin plugs that resemble comedones, but they are not actually comedones.

As nevus comedonicus is an asymptomatic benign condition, no treatment is required. Surgical excision of small lesions can be curative and should be considered in consultation with a dermatologic/plastic surgeon. Incomplete excision may result in recurrence of the lesion. Laser surgery has been tried.

Nevus sebaceous syndrome can result in eye tumours and the skull may be asymmetrical. Characteristic associated neurological features include: Developmental delay. Epileptic seizures, especially infantile spasms.

With basal cell nevus syndrome, the first mutation is inherited from either the mother or the father. This happens in 70% to 80% of cases. In 20% to 30% of cases, the first mutation is not inherited. It arises for the first time (de novo) in the affected person.

Congenital melanocytic nevi do not go away with time. Some congenital melanocytic nevi may get lighter in color over the first few years of life.

The prognosis associated with any single melanocytic nevus is favorable because these lesions are benign neoplasms with no potential for malignant behavior, unless evolution of melanoma occurs.

What is a birthmark that looks like a blackhead? ›

A comedo naevus (comedo nevus), also known as naevus comedonicus, is a rare, benign, cutaneous anomaly consisting of grouped, dilated follicular openings containing soft, dark keratin that resemble comedones.

A nevus sebaceous will appear as a yellow-orange patch of skin that is hairless and smooth. It's circ*mscribed, meaning that it has well-defined borders, and is likely to appear either oval or linear in shape. Typically, there will be just one patch of skin affected, and it may look like a plaque.

Epidermal nevus syndromes (ENSs) are a group of rare complex disorders characterized by the presence of skin lesions known as epidermal nevi associated with additional extra-cutaneous abnormalities, most often affecting the brain, eye and skeletal systems.

During early development stages, budworm larvae are creme-colored with a distinct black head. Their body color changes to green as they develop and the head capsule is brown during the last development stage (Fig.

This phenomenon is called a "pore of Winer," and it's an actual thing. It's just a fancy term for a very big blackhead or whitehead. So now not only do we have to fear those nasty things, but these giant, raised rock pimples can cause a lot of trouble. It certainly did for this patient.

What Is the White Stuff That Comes Out When You Squeeze Your Nose Pores? The white stuff that comes out of your pores like thin strings when you squeeze your nose is called a sebaceous filament. It's mostly made up of sebum (oil that your skin produces) and dead skin cells.

Large congenital melanocytic nevi are associated with an increased risk for developing cutaneous melanoma, leptomeningeal melanoma, neurocutaneous melanocytosis, malformations of the brain, and, rarely, rhabdomyosarcoma and liposarcoma.

However, sometimes nevi under the center of the retina (the macula) can cause blurred vision. When a nevus causes degeneration or dysfunction of the overlying RPE, fluid may accumulate under the retina or abnormal blood vessels (choroidal neovascularization) may develop and bleed or leak fluid.

Keloidlike plaques, scarring alopecia, chronic draining sinuses, and bacterial infection are complications of acne keloidalis nuchae (AKN).